The brain is still ‘connected’ during non-REM sleep

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Although historically this concept has been studied from a philosophical standpoint, experts have reviewed various scientific studies which reflect the importance of a proper communication between cortical areas in the process.

“Neuroscientific research on consciousness driven by new methods and theoretical advances should be increasingly robust and accepted, since notable scientific and clinical progress is now starting to be made,” the authors pointed out.

The CANON project is a partnering project of the Human Brain Project, one of the Future Emerging Technology Flagship Initiatives (FET Flagships) of Horizon 2020 – the European Union framework programme for financing research.

Inserm (the French National Institute of Health and Medical Research) and the Wigner Research Centre for Physics (Hungary) participate in the CANON project alongside the University of Amsterdam.


Umberto Olcese, Jeroen J. Bos, Martin Vinck, Jan V. Lankelma, Laura B. van Mourik-Donga, Friederike Schlumm and Cyriel M.A. Pennartz. “Spike-Based Functional Connectivity in Cerebral Cortex and Hippocampus: Loss of Global Connectivity Is Coupled to Preservation of Local Connectivity During Non-REM Sleep”, The Journal of Neuroscience, July 2016, 36 (29). DOI: 10.1523/JNEUROSCI.4201-15.2016.

Joahn F. Storm, Mélanie Boly, Adenauer G. Casali, Marcello Massimini, Umberto Olcese, Cyriel M.A. Pennartz and Melanie Wilke. “Consciousness Regained: Disentangling Mechanisms, Brain Systems, and Behavioral Responses”, The Journal of Neuroscience, November 2017, 37 (45). DOI: 10.1523/JNEUROSCI.1838-17.2017.

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