Mamadou Sakho, Aaron Wan-Bissaka and Alexander Sørloth will be meeting fans at a special hour-long signing session at the shop on Thursday (November 8).
The free to attend event will run between 3.30 and 4.30pm.
The new store is on the ground floor of Centrale and opened for the first time last Monday (November 5). It offers replica kits, Palace clothing ranges and plenty of club merchandise.
Palace have said the signing session is expected to be “extremely popular”, so anyone wanting to meet the players should arrive early.
“A queue management system will be in place, and signings will be done on a first-come, first-served basis,” a spokesman for the club said.
“Please ensure that you arrive with plenty of time to give yourselves the best chance of meeting a player.”